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2013•Zhongguo yiyuan ganranxue zazhiRequires access

Drug resistance of Acinetobacter baumanniiin ICU

Qinghe Hu

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Abstract

OBJECTIVE To analyze the drug resistance of the A.baumannii in ICU so as to guide the reasonable use of antibiotics.METHODS The drug resistance rates of 146 clinical isolates of A.baumannii isolated in the first half of 2011 were retrospectively analyzed.RESULTS Of the 146 strains of A.baumannii,the specimens of lower respiratory tract were the predominant source,accounting for 93.15%;the drug resistance rate was higher than 52.74% to all the antibiotics except cefoperazone/sulbactam and minocycline,and the drug susceptibility rate to cefoperazone/sulbactam was the highest(56.85%);the isolation rate of the multidrug-resistant strains increased from 44.4% to 62.33% in 2009.CONCLUSION The drug resistance of the A.baumannii and the incidence of multidrug-resistant bacteria infections in the ICU show an upward trend,and cefoperazone/sulbactam has good antibacterial activity against the A.baumannii.

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OBJECTIVE To analyze the drug resistance of the A.baumannii in ICU so as to guide the reasonable use of antibiotics.METHODS The drug resistance rates of 146 clinical isolates of A.baumannii isolated in the first half of 2011 were retrospectively analyzed.RESULTS Of the 146 strains of A.baumannii,the specimens of lower respiratory tract were the predominant source,accounting for 93.15%;the drug resistance rate was higher than 52.74% to all the antibiotics except cefoperazone/sulbactam and minocycline,and the drug susceptibility rate to cefoperazone/sulbactam was the highest(56.85%);the isolation rate of the multidrug-resistant strains increased from 44.4% to 62.33% in 2009.CONCLUSION The drug resistance of the A.baumannii and the incidence of multidrug-resistant bacteria infections in the ICU show an upward trend,and cefoperazone/sulbactam has good antibacterial activity against the A.baumannii.

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Available abstract

OBJECTIVE To analyze the drug resistance of the A.baumannii in ICU so as to guide the reasonable use of antibiotics.METHODS The drug resistance rates of 146 clinical isolates of A.baumannii isolated in the first half of 2011 were retrospectively analyzed.RESULTS Of the 146 strains of A.baumannii,the specimens of lower respiratory tract were the predominant source,accounting for 93.15%;the drug resistance rate was higher than 52.74% to all the antibiotics except cefoperazone/sulbactam and minocycline,and the drug susceptibility rate to cefoperazone/sulbactam was the highest(56.85%);the isolation rate of the multidrug-resistant strains increased from 44.4% to 62.33% in 2009.CONCLUSION The drug resistance of the A.baumannii and the incidence of multidrug-resistant bacteria infections in the ICU show an upward trend,and cefoperazone/sulbactam has good antibacterial activity against the A.baumannii.

Key concepts: Acinetobacter baumannii, Cefoperazone, Sulbactam, Drug resistance, Antibiotics, Multiple drug resistance, Medicine, Microbiology

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