Effect of naoxintong capsules combined with rosuvastatin on blood lipid and blood rheology of patients with cerebral infarction combined with carotid atheromatous plaque

Objective To explore the effect of naoxintong capsules combined with rosuvastatin on blood lipid and blood rheology of patients with brain infarction combined with carotid atheromatous plaque. Methods 104 patients with brain infarction complicated with carotid atheromatous plaque were randomly and equally divided into control group and treatment group,control group was given rosuvastatin( 10 mg /d,once daily),on the basis of the control group,the treatment group was given naoxintong capsules( 1. 2 g per time,3 times daily),with treatment period of six months of the two groups,blood lipid and blood rheology indexes before and after treatment in two groups were observed. Results TC,TG,LDL-C,HDL-C of the two groups after treatment had obvious difference from those before treatment( P 0. 05),after treatnent there were significant differences in TC,TG,LDL-C,HDL-C between the two groups( P 0. 05). After treatment,blood rheology indexes of the two groups obviously decreased( P 0. 05),hemorheology index change values of the treatment group were respectively greater than those of control group( P 0. 05).In the two groups the total artery IMT and carotid plaque integral,NIHSS score,MRS score after treatment were significantly lower,and Barthel index increased obviously,significart difference was observed in IMT and carotid plaque integral,NIHSS score,MRS score and Barthel index between the two groups( P 0. 05). Conclusion Naoxintong capsule and rosuvastatin can obviously improve the blood lipid and blood rheology indexes,lower TC,TG,LDL-C,make atherosclerotic plaque stability,improve brain function of patients with cerebral infarction complicated with carotid atheromatous plaque.