Clinical application value of intravascular ultrasound in the diagnosis and treatment for intermediate lesions showed by coronary angiography

Objective To investigate the clinical application value of intravascular ultrasound(IVUS)in the diagnosis and treatment for intermediate atherosclerotic lesions showed by coronary angiography(CAG).Methods IVUS was performed in 62 lesions of 54 patients,the total vessel area(TVA),minimal lumen area(MLA),area stenosis(%AS),reference lumen diameter(RLD),vessel diameter(VD),minimal lumen diameter(MLD)and diameter stenosis(%DS)were measured.Interventional therapy was performed based on the IVUS and clinical findings.The IVUS parameters and morphological characteristics were compared between 26 lesions in 30 patients with intervention therapy and 28 lesions in 32 patients without intervention therapy.In patients with standing,the IVUS parameters before and after standing were compared.Results CAG showed that the MLD,%DS and %AS were significantly lower than those obtained by IVUS(P0.05).CAG could only demonstrate the morphological characters of the arterial lumen,while IVUS could reveal the characteristics of the lesion on the vessel wall at the same time.The intervention group had more severe stenosis with mean %AS of 71.4%,consistent with the indication of percutaneous coronary intervention(PCI)and the %AS was significantly higher than that in patients without intervention therapy(39.6%,P0.05).Meanwhile,the parameters before and after standing were measured by IVUS.The MLA,%AS,MLD and %DS after standing were significantly higher than those before intervention therapy(P0.05),however,there were no significant changes in TVA and VD(P0.05).Conclusion IVUS is superior to CAG in the assessment of the intermediate lesions,since which could demonstrate the characteristics of the lesion,and could provide guidance for the treatment plan and evaluate the interventional results.