Comparison study of echocardiography with or without low dose dobutamine stress combined with integrated backscatter and Doppler tissue image for identifying survival myocardium in patients with coronary artery disease

Objective:To compare the accuracy of low dose dobutamine(Dob) stress echocardiography(LDDSE) combined with integrated backscatter(IBS) and that combined with Doppler tissue image(DTI) for identifying survival myocardium in patients with coronary artery disease(CAD).Methods:Percutaneous coronary intervention(PCI) was performed in 18 patients for CAD by quantitative coronary artery(QCA).LDDSE was applied and images and parameters IBS or DTI were obtained before a week of PCI.Two-dimensional echocardiography was penfomed after three months of PCI again.Defining the maximumal changing rate of CVIB(K) of IBS(during LDDSE 13) and the maximumal change of Vs(K) of(DTI during LDDSE 2cm/s) were defined as survival myocardium and then the accuracies in identifying survival myocardium were compared among LDDSE.IBS combined with LDDSE,and DTI combined with LDDSE.Results:The sensitivity,specificity,accuracy for identifying survival myocardium by LDDSE combined with IBS and DTI were significantly higher than those of LDDSE(5,10μg/(Kg.min))(P40.05～0.01),as well as compared with DTI,the sensitivity,accuracy were 86.7%,87.1% Vs 78.9%,79.1% and significantly improved respectively by LDDSE+IBS(P0.05).The specificity of LDDSE combined with DTI was than that of LDDSE combined with IBS(87.5% Vs 81.3%)(P0.05).Conclusion:Identifying survival myocardium by LDDSE combined with IBS have a higher value than those of LDDSE combined with DTI alone.