Low dose dobutamine stress echocardiography combined with integrated backscatter for identifying survival myocardium in patients with coronary artery disease

Objective To compare the accuracy of low dose dobut amine(Dob) stress echocardiography(LDDSE) and combination of integrated backscatter(IBS) for identifying survival myocardium in patients with coronary artery disease(CAD). Methods Percutaneous coronary intervention(PCI) was performed in 18 patients which were admitted for CAD by quantitative coronary artery(QCA). LDDSE was checked and IBS images were obtained before a week of PCI. Two-dimension echocardiography was examined after three months of PCI again. Defining the maximumal changing rate of CVIB(K) during LDDSE 13 as survival myocardium, then the accuracies in identifying survival myocardium were compared between LDDSE and LDDSE+IBS. Results The sensitivity, accuracy for identifying survival myocardium were significantly higher by LDDSE combined with IBS than those of LDDSE [5, 10 μg·kg -1·min -1] ( sensitivity: 91.84% vs 79.6%、 85.7%, P 0.05- 0.01),accuracy: 91.07 vs 78.9%、 85.7% respectively P 0.05- 0.01). Conclusion Identifying survival myocardium by LDDSE combined with IBS was more sensitive, accurate than LDDSE alone.