2014China Foreign Medical TreatmentRequires access

Feasibility Analysis of Different Doses of Atorvastatin Treatment for Elderly Patients with Coronary Heart Disease

Li We

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Abstract

Objective To analyze the feasibility of the implementation of different doses of atorvastatin in the treatment of elderly patients with coronary heart disease. Methods A total of 80 cases admitted in our hospital were randomly divided into the control group and the observation group. The patients in group A were mainly given 40 mg atorvastatin for clinical treatment, and patients in group B were given 20 mg atorvastatin for treatment. And the treatment effect was observed in two groups. Results After treatment, TG, TC and LDL-cC levels of the two groups were associated with a certain degree of decline, the differences in TG, TC and LDL-cC levels of the two groups before and after treatment were statistically significant(both P0.05); after treatment, the elevated HDL-C level of group A was(1.24±0.39), significantly higher than that(1.12±0.41) of group B, the decreased level of TG, TC and LDL-cC of group A was(1.10±0.43),(3.30±0.65) and(1.06±0.49), respectively, significantly lower than(1.38±0.47),(4.42±0.64) and(1.65±0.42) of group B, respectively, the differences were statistically significant(all P0.05). The difference in the incidence of adverse reactions between the two groups was not statistically significant, P0.05. Conclusion The therapeutic effect of high dose atorvastatin for elderly coronary heart disease is better than that of low dose atorvastatin.

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Objective To analyze the feasibility of the implementation of different doses of atorvastatin in the treatment of elderly patients with coronary heart disease. Methods A total of 80 cases admitted in our hospital were randomly divided into the control group and the observation group. The patients in group A were mainly given 40 mg atorvastatin for clinical treatment, and patients in group B were given 20 mg atorvastatin for treatment. And the treatment effect was observed in two groups. Results After treatment, TG, TC and LDL-cC levels of the two groups were associated with a certain degree of decline, the differences in TG, TC and LDL-cC levels of the two groups before and after treatment were statistically significant(both P0.05); after treatment, the elevated HDL-C level of group A was(1.24±0.39), significantly higher than that(1.12±0.41) of group B, the decreased level of TG, TC and LDL-cC of group A was(1.10±0.43),(3.30±0.65) and(1.06±0.49), respectively, significantly lower than(1.38±0.47),(4.42±0.64) and(1.65±0.42) of group B, respectively, the differences were statistically significant(all P0.05). The difference in the incidence of adverse reactions between the two groups was not statistically significant, P0.05. Conclusion The therapeutic effect of high dose atorvastatin for elderly coronary heart disease is better than that of low dose atorvastatin.

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Available abstract

Objective To analyze the feasibility of the implementation of different doses of atorvastatin in the treatment of elderly patients with coronary heart disease. Methods A total of 80 cases admitted in our hospital were randomly divided into the control group and the observation group. The patients in group A were mainly given 40 mg atorvastatin for clinical treatment, and patients in group B were given 20 mg atorvastatin for treatment. And the treatment effect was observed in two groups. Results After treatment, TG, TC and LDL-cC levels of the two groups were associated with a certain degree of decline, the differences in TG, TC and LDL-cC levels of the two groups before and after treatment were statistically significant(both P0.05); after treatment, the elevated HDL-C level of group A was(1.24±0.39), significantly higher than that(1.12±0.41) of group B, the decreased level of TG, TC and LDL-cC of group A was(1.10±0.43),(3.30±0.65) and(1.06±0.49), respectively, significantly lower than(1.38±0.47),(4.42±0.64) and(1.65±0.42) of group B, respectively, the differences were statistically significant(all P0.05). The difference in the incidence of adverse reactions between the two groups was not statistically significant, P0.05. Conclusion The therapeutic effect of high dose atorvastatin for elderly coronary heart disease is better than that of low dose atorvastatin.

Key concepts: Atorvastatin, Medicine, Coronary heart disease, Internal medicine, Incidence (geometry), Group B, Gastroenterology, Significant difference

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