The checking worthiness of the blood Cystatin-C in the early renal function damage

Objective To discuss the using worthiness of the blood Cystatin-C(Cys-C) checking in the early kidney damage.Methods Two hundred and fifty three patients were chosen and were divided into renal function normal group(Group A),mild kidney damage group(Group B),moderate kidney damage group(Group C) and serious kidney damage group(Group D) 4 groups according to the creatinine clearance rate,60 cases were chosen in the control group,the chroma of Cys-C was checked using grain enhancement scattering immunifaction,at the same time,the serum creatinine(Scr),blood urea nitrogen(BUN) and creatinine clearance rate(Ccr) were checked using the enzymic method,and then the blood Cys-C、Scr and BUN in each group were compared and analyzed.Results In the kidney damage patients,renal function normal group(Group A) and mild kidney damage group(Group B),only Cys-C had statistical significance with the health group(P 0.01),and the Cys-C,Scr and BUN in the moderate kidney damage group(Group C) and serious kidney damage group(Group D) had statistical significance with the health group(P 0.01 or P 0.05).Conclusion The blood Cys-C is an acute diagnosticate index in the early kidney damage,can estimate glomerular filtration function damage early.