Change of cognitive function and analysis of related factors in schoo-age children with epilepsy

Objective To study the cognitive function and related factors in school-age patients with epilepsy. Methods To investigate the data of 38 cases of seizure control in more than 75% and more than one year of school-age children with epilepsy clinical ther are diaghosed in our hospital., all children with epilepsy before and after treatment cognitive function were measured by Wechsler Intelligence Scale for Children compared with 30 normal control children, and conduct the final statistical analysis.Results IQ of children with epilepsy compared with normal control group decreased significantly(P0.01); epilepsy after treatment in patients with a total IQ and course of disease, seizure frequency, time of each attack was positively correlated (γ= 0.523, P = 0.013; γ= 0.432, P = 0.043; γ= 0.487, P = 0.048), and the age at onset was negatively correlated (γ=-0.452, P= 0.046); epileptic seizures in children with single-drug therapy to manage are year after the average IQ from 81.97 to 90.93,there was statistically significant (P0.05), the average IQ using two drugs from 85.89 to 88.78, no statistical significance .Conclusion Intelligence in children with epilepsy are different degrees of impairment, and the at onset and duration, seizure frequency and duration of each attack is related to it,drug control seizures in children is benefits on the cognitive function.