A Baseline Survey on Serological Epidemiology for the Integration of Hepatitis B Vaccine into the Expended program on Immunization in Guangxi

To get baseline data for the implementation of the integration of hepatitis B vaccine(HepBV)into the Expended Program on Immunization,a multistage cluster-randomized sampling was designed to survey 5 670 children aged 0～3 years and 1 216 mothers in 2003 The results revealed that the HepBV coverage,full dose coverage and the first dose timely coverage among the children were 76 16%,73 44% and 32 66% respectively;the HBsAg positive rate,anti-HBsAg positive rate and anti-HBc positive rate were 3.37%,40.18% and 5.17% respectively. As compared with the survey in 1992,HepBV coverage increased 77 61% and the HBsAg carrier rate dropped from 9 86% to 3 37%, the protection rate was 65 19% The HBsAg positive rate and anti-HBc positive rate among the children who had received a timely birth dose and full dose vaccination were observed to be considerably lower than those among the unvaccinated children Among the children of the HBsAg positive the HBsAg positive rate and anti-HBc positive rate were significantly higher than those among other children The hepatitis B control should focus on improving the first dose timely coverage and full dose coverage and also on decreasing the HBsAg positive rate and anti-HBc positive rate among the children whose mothers are HBsAg positive