2006Central Plains Medical JournalRequires access

Changes of BAEP in newborns with hypoxic ischemic encephalopathy

Qin Qingya

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Abstract

Objective To make a researsh on the changes of cerebral auditory centre and the peripheral transmission in newborns with HIE.Methods We tested the BAEP(brain-stem auditory evoked potential) of 50 cases being diagnosed as neonatal HIE.Of the 50 cases,the mild HIE was 36 cases,the serious HIE was 14 cases.The result were compared to the BAEP of 52 normal neonates.Results In HIE group,the rate of abnormity of BAEP was 58%,in normal group,the rate of abnormity was 1.9%.There was statistical difference between the two groups.In the mild HIE group,the rate of abnormity was 44.4%,peripheral auditory damage was main,I wave deletion and the peak latencies of wave were prolonged,autory threshold rising.In the serious HIE group,the rate of abnormity was 78.6%,central auditory damage was main,abnormity BAEP always had duplication,each wave disappeared,the peak latencies(PL) and the inter-peak latencies(IPL) were prolonged.In the group of HIE there were 46 cases tested by encephalogram,27 cases were abnomal,the abnomality rate was 58.7%,it was parallel comparing the change of BAEP.Having being treated,6 months later,the peripheral auditory damage infants of BAEP were restored normal.Four cases of the central damage are not restored yet.Conclusion BAEP has significant meaning in evaluating the autory and brainstem functions of newborns with HIE.The peripheral auditory damage is reversible.So we suggest that the BAEP of neonatal HIE should be tested as early as possible.Early discovery,early treating is active to prevent affecting the development of the infant's language and mind.

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Objective To make a researsh on the changes of cerebral auditory centre and the peripheral transmission in newborns with HIE.Methods We tested the BAEP(brain-stem auditory evoked potential) of 50 cases being diagnosed as neonatal HIE.Of the 50 cases,the mild HIE was 36 cases,the serious HIE was 14 cases.The result were compared to the BAEP of 52 normal neonates.Results In HIE group,the rate of abnormity of BAEP was 58%,in normal group,the rate of abnormity was 1.9%.There was statistical difference between the two groups.In the mild HIE group,the rate of abnormity was 44.4%,peripheral auditory damage was main,I wave deletion and the peak latencies of wave were prolonged,autory threshold rising.In the serious HIE group,the rate of abnormity was 78.6%,central auditory damage was main,abnormity BAEP always had duplication,each wave disappeared,the peak latencies(PL) and the inter-peak latencies(IPL) were prolonged.In the group of HIE there were 46 cases tested by encephalogram,27 cases were abnomal,the abnomality rate was 58.7%,it was parallel comparing the change of BAEP.Having being treated,6 months later,the peripheral auditory damage infants of BAEP were restored normal.Four cases of the central damage are not restored yet.Conclusion BAEP has significant meaning in evaluating the autory and brainstem functions of newborns with HIE.The peripheral auditory damage is reversible.So we suggest that the BAEP of neonatal HIE should be tested as early as possible.Early discovery,early treating is active to prevent affecting the development of the infant's language and mind.

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Available abstract

Objective To make a researsh on the changes of cerebral auditory centre and the peripheral transmission in newborns with HIE.Methods We tested the BAEP(brain-stem auditory evoked potential) of 50 cases being diagnosed as neonatal HIE.Of the 50 cases,the mild HIE was 36 cases,the serious HIE was 14 cases.The result were compared to the BAEP of 52 normal neonates.Results In HIE group,the rate of abnormity of BAEP was 58%,in normal group,the rate of abnormity was 1.9%.There was statistical difference between the two groups.In the mild HIE group,the rate of abnormity was 44.4%,peripheral auditory damage was main,I wave deletion and the peak latencies of wave were prolonged,autory threshold rising.In the serious HIE group,the rate of abnormity was 78.6%,central auditory damage was main,abnormity BAEP always had duplication,each wave disappeared,the peak latencies(PL) and the inter-peak latencies(IPL) were prolonged.In the group of HIE there were 46 cases tested by encephalogram,27 cases were abnomal,the abnomality rate was 58.7%,it was parallel comparing the change of BAEP.Having being treated,6 months later,the peripheral auditory damage infants of BAEP were restored normal.Four cases of the central damage are not restored yet.Conclusion BAEP has significant meaning in evaluating the autory and brainstem functions of newborns with HIE.The peripheral auditory damage is reversible.So we suggest that the BAEP of neonatal HIE should be tested as early as possible.Early discovery,early treating is active to prevent affecting the development of the infant's language and mind.

Key concepts: Brainstem auditory evoked potential, Medicine, Brain damage, Encephalopathy, Brainstem, Audiology, Peripheral, Anesthesia

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