2001•Sichuan Journal of Cancer ControlRequires access

Apoptosis of Cancer cells Induced by Influenza Virus -preliminary Study

Li Hua

Abstract

Objective:To observe the apoptosis of cancer cells induced by influenza virus.Methods:Hela and Raji cells cultured in vitro were infected by influenza virus and their apoptosis profiles were observed and detected at different times after infection.Results:The infected cells showed apparent changes in growth characteristics and morphologies;DNA agarose gel electrophoresis showed characteristic “ladder;Apoptosis peaks were observed by flow cytometry;and the apoptosis ratios were proportional to the times of post infection.Conclusion:Influenza virus can induce Hela and Raji cells to undergo apoptosis in vitro.

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Key concepts: Apoptosis, HeLa, Raji cell, Virus, Flow cytometry, Agarose gel electrophoresis, In vitro, Molecular biology