Detection of Mycoplasma and Chlamydia Caused Urogenital Tract Infection in 1 203 Patients and Their Antibiotic Susceptibilities Study

Objective The incidences of urogenital tract infection caused by Ureaplasma urealyticum (Uu), Mycoplasma hominis (MH)and Chlamydia trachomahs (CT) and their susceptibilities to 12 antibiotic agents were reviewed. Method CT, Uu and MH were cultured and their drug susceptibilities from 1,203 patients with urogenital tract infections were statistically analyzed. Results In the 1,203 specimens, 61.9% patients(745 cases) were infected by CT, Uu and MH, the positive rate in women was 70.9%(524 cases) and 44.3%(221 cases) in men; 13.7% patients were CT positive. The positive rate of Uu in women(46.4%) was statistically higher than that in men (28.1%).The mixed infected rate with Uu and MH in women (12.55%) was higher than that in men (2.4%) too. Drug sensitivities to Doxycyciine, Minocin, Josanmycin, Davercin, and Clarithromycin for Uu were over 90%, and susceptability to Quinolones was under 50%. Drug sensitivities to Rocithromycin, Erythromycin, and Ciprofloxacin in mixed infection of Uu and MH were very poor at all. Drug sensitivity to Un infection was different from that of the mixed infection of Uu and MH. Conclusions Mycoplasma infection in urogenital tract is mainly caused by Uu infection, and followed by CT and mixed infection with Uu and MH. The positive rate in women was predominant. Pure Uu infection shows a significant difference with Uu and MH combined infection on drug susceptibilities. It is important to develop antibiotic susceptility test in addition to mycoplasma culture in patients with urogenital tract infection in guiding selection of appropriate antibiotic chemotherapy.