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2008•Journal of Medical ForumRequires access

Study on Rrimebutine Maleate in Treatment of Irritable Bowel Syndrome

Xiaoling Liu

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Abstract

Objective To study the effects of trimebutine maleate and antidepressants in treating irritable bowel syndrome(IBS).Methods Total 164 irritable bowel syndrome(IBS) patients were resistant to routine treatment.This study consisted of a 4-week randomized treatment period with trimebutine maleate 0.1 tid and doxepin 12.5mg qn.followed by a 4-week withdrawal follow-up observation period. Results After treated with trimebutine maleate,the overall sympton were ameliorated,The total efficacy rate were 98.78%.Conclusion Trimebutine maleate uniting doxepin is an effective and safe medicine for alleviation of IBS symptoms.

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What this paper is about

Objective To study the effects of trimebutine maleate and antidepressants in treating irritable bowel syndrome(IBS).Methods Total 164 irritable bowel syndrome(IBS) patients were resistant to routine treatment.This study consisted of a 4-week randomized treatment period with trimebutine maleate 0.1 tid and doxepin 12.5mg qn.followed by a 4-week withdrawal follow-up observation period. Results After treated with trimebutine maleate,the overall sympton were ameliorated,The total efficacy rate were 98.78%.Conclusion Trimebutine maleate uniting doxepin is an effective and safe medicine for alleviation of IBS symptoms.

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Available abstract

Objective To study the effects of trimebutine maleate and antidepressants in treating irritable bowel syndrome(IBS).Methods Total 164 irritable bowel syndrome(IBS) patients were resistant to routine treatment.This study consisted of a 4-week randomized treatment period with trimebutine maleate 0.1 tid and doxepin 12.5mg qn.followed by a 4-week withdrawal follow-up observation period. Results After treated with trimebutine maleate,the overall sympton were ameliorated,The total efficacy rate were 98.78%.Conclusion Trimebutine maleate uniting doxepin is an effective and safe medicine for alleviation of IBS symptoms.

Key concepts: Doxepin, Irritable bowel syndrome, Medicine, Anesthesia, Internal medicine

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