Clinical Efficacy of Restructuring hEGF Treatment for Dry Eye after Diabetic Cataract Phacoemulsification

Objective The purpose of this study was to investigate the clinical efficacy of restructuring hEGF treatment for dry eye after diabetic cataract phacoemulsification. Methods Seventy-six patients with diabetic cataract(96 eyes) were randomly divided into control group and observation group. Patients in control group were given artificial tears therapy,and patients in the observation group were treated with artificial tears plus hEGF. The subjective symptom scores, tear film breakup time(BUT) measurement, Schirmer test(SIt), and corneal fluorescein staining(FL) were measured. Res ults The symptoms of dry eye at 1w after treatment have significant improved compared with those at 1d in both two groups(P 0.05). There were significant differences in the symptoms of dry eye at 4w compared with those at 1w and 1d after treatment(P 0.05).Compared with the control group,the significant improvement of symptoms was found in observation group after 1w and 4w treatment(P 0.05). In the control group, BUTat 4wwas significantlyimproved than that at 1d and 1w(P 0.05). In the observation group,BUT at 1w and 4w were significantly improved than that at 1d(P 0.05). Compared with the control treatment,BUT showed significant improvement after 1w and 4w treatment in the observation group(P 0.05). Compared with postoperative 1d,SIt of patients showed significant improvement at 4w in the control group(P 0.05). In the observation group,SIt at 1wand 4wwere significantly improved than that at 1d(P 0.05), and there was significant difference compared with the control group after 1w treatment(P 0.05). The FL of patients at 1w and 4w after treatment have significant improved compared with that at 1d in both two groups(P 0.05). Compared with the control treatment, FL showed significant improvement at the same period in the observation group(P 0.05). Conclus ion Restructuring hEGF treatment can improve dry eye symptoms in diabetes mellitus after phacoemulsification, and it is important to promote postoperative recovery.