2012•Unpublished venueRequires access
Gastric cancer and precancerous lesions associated with Helicobacter pylori infection
Wenjie Jin
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Abstract
Objective:To determine the Helicobacter pylori infection in atrophic gastritis,intestinal metaplasia,dysplasia and gastric infection.Methods: Atrophic gastritis and intestinal metaplasia(A group)were 342 cases,the opposite sex hyperplasia(B group)229 cases of gastric cancer patients(C group)298 patients,were detected for serum anti-Hp-IgG antibodies by ELISA kit.Results: Dysplasia and gastric cancer with Hp infection rate was higher than the atrophic gastritis group(P0.05).Helicobacter pylori infection and atrophic gastritis,intestinal metaplasia and hyperplasia of the opposite sex than non-cancerous Helicobacter pylori infection was differ rent significantly,P0.05;for cancer patients with helicobacter pylori infection,5-year survival rate was significantly shorter than the H.Lo non-infected patients P0.05.Conclusion: Hp infection and atrophic gastritis,intestinal metaplasia,dysplasia and gastric cancer are closely related,and reduce atrophy gastritis,intestinal metaplasia,dysplasia,shorten the five-year cancer survival rate.