Mycoplasma and chlamydia infections in urogenital tract and drug susceptibility test

OBJECTIVE To investigate the infection and drug resistance of urogenital mycoplasma and chlamydia in the patients with suspected nongonocoeeal urethritis(NGU).METHODS Ureaplasma urealytieum(Uu) and Mycoplasma hominis(Mh) as well as their drug susceptibilities were tested by using the mycoplasma detection kits.Chlamydia antigen Was detected by the Colloidal gold method.RESULTS The total infection rate of mycoplasma was 56.76%in 1012 patients with suspected NGU.Only Uu positive rate(46.5%) was higher than Uu and Mh positive rate(7.4%) and only Mh positive rate(2.49%)(P0.01).Ct positive rate(13.2%).The highest resistant rates to erythromycin and Ofloxacin were 76.7% and 80.0%;the sensitive rates to doxycycline and minocycline were 75.5%,and 73.3% respectively.In Mh infections,sensitivity rates to josamylin,minocycline,doxycycline and thiamphenicol were 81.4%,69.9%,67.3% and 51.2%,respectively.CONCLUSIONS Vibramycin,josamycin,minocycline and thiamphenicol can be used as initial therapy in the region for mycoplasma infection.And antimicrobial agents should be chosen according to antimicrobial susceptibility test results.The infection of Uu is common in the patients of NGU.Mornitoring the drug resistance play an important guide role in the clinical treatment.