Analysis of infection patterns and drug-resistance of urogenital mycoplasma and Chlamydia isolated from 680 female patients

Objective To explore the situation of urogenital mycoplasma and chlamydia infection and drug-resistance in 680 female patients Methods Chlamydia antigen in clinical specimens was detected by McAb with colloidal gold-labeled(MACG) technique,mycoplasma were cultured and antimicrobial drug-susceptibility were detected.Results In 680 cases urogenital samples,35 cases were chlamydia trachomatis positive(5.2%),320 were mycoplasma positive(47.1%).There were 255 cases of urealyticum ureaplasma(Uu) with a positive rate of 37.5% and 17 cases of mycoplasma hominis(Mh) with a positive rate of 2.5%,dual infection of Uu and Mh were 48 cases and the mixed positive rate was 7.1%;the results of drug sensitivity showed that most of Un and Mh were sensitive to josamycin,doxycycline and minocycline,and the drug-resistance rate of them to Ofloxacin,levofloxacin,sparfloxacin,and clindamycin was the highest.Conclusions Uu infection was the most cause in female urogenital and genital tract infection,and it was multi-drug resistant.It should refer to the results of antimicrobial drug-susceptibility to minimize the generation of resistant strains,josamycin,doxycycline and minocycline were the first choice of clinical mycoplasma infection.