Analysis of clinical antibiotic resistance of common pathogenic bacteria in a hospital from2010to 2012

Objective To analyze the drug resistance of clinical common pathogenic bacteria in this hospital.Methods Results of drug sensitive test of pathogenic bacteria during Jan.2010and Dec.2012were retrospectively analyzed.Results A total of 10 153strains of bacteria were isolated within the three years,among which Gram negative bacilli accounted for 61.2%,Gram positive bacteria accounted for 26.6%,fungi accounted for 12.2%.The most common six kinds of pathogenic bacteria were Pseudomonas aeruginosa(16.6%),Escherichia coli(15.0%),Klebsiella pneumoniae(11.6%),Candida albicans(9.8%),Acinetobacter baumannii(5.1%),and Staphylococcus aureus(4.1%).Gram negative bacteria were sensitive to imipenem,amikacin,piperacillin/Tazo,and resistant to ampicillin and compound sulfamethoxazole.Gram positive bacteria were sensitive to vancomycin and piperacillin/Tazo,but resistant to erythromycin and ampicillin.Candida albicans were sensitive to amphotericin B,nystatin and 5-flurocytosine.Conclusion The most common pathogenic bacteria isolated in this hospital might be gram negative bacteria.More attention should be paid for the monitoring of drug resistance of pathogenic bacteria.Antibiotics should be rationally used in the treatment.