Relationship between chlamydia trachomatis or ureaplasma urealyticum infection and pelvic adhesion

Objective To investigate the relationship between Chlamydia trachomatis (CT) or Ureaplasma urealyticum (UU) infection and pelvic adhesion. To explore the mechanism of pelvic adhesion and the possible approach to reduce the incidence of pelvic adhesion. Methods 50 women with pelvic adhesion in laparoscopic of abdominal operation (study group) and 40 women without pelvic adhesion in the same period (control group) were recruited in this study. Cervical discharge samples and operational samples were collected and CT DNA and UU DNA were detected by polymerize chain reaction (PCR). Serum samples were used to detect CT antibody and UU antibody by gold-labeled immunospot. Results CT DNA and UU DNA were detected in cervical discharge at rates of 32% and 40% respectively in the study group, and 7.5% and 1% respectively in the control group. The positive rate of CT-Ab and UU-Ab in the study group were 34% and 48% respectively, 5% and 10.25% in the control group respectively. CT DNA and UU DNA were detected in operational samples at rates of 26% and 15% respectively, and 2.5% and 5% in controls. All of the differences between the study group and control were statistically significant (P0.01). Conclusions Chlamydia trachomatis (CT) and Ureaplasma urealyticum (UU) infections were correlated with pelvic adhesion.