ScholarLens Back to search
2007•Journal of Emergency in Traditional Chinese MedicineRequires access

The Effects of Astragus on the Neuronal Apoptosis and the Expression of JUN Protein after Cerebral Ischemia Reperfusion

Qu You

Open publisher page 0 citations

Abstract

Objective:To investigate the effiects of astragus on neuronal apoptosis and the expression of JUN protein after cerebral ischemia and reperfusion,probe the mechanism of astragus Preventing against cerebral ischemia-reprefusion injury. Methods:Methods of TUNEL and immunohistochenfistry were used respectively to measure neuronal apoptotmc cells and the expression of JUN protein in rats’ brains.Results:Compared with those in the sham-operated group, the numbers of neuronal apoptotic and JUN protein positive cells increased markedly in the model group.Compared with those in the model group, the nunlbers of neuronal apoptotic and JUN protein positive cells were less in the astragus group. Conclusion:Astragus could decrease neuronal apoptosis after cerebral ischemia and reperfusion by inhibiting the expression of JUN protein.

About this research paper

What this paper is about

Objective:To investigate the effiects of astragus on neuronal apoptosis and the expression of JUN protein after cerebral ischemia and reperfusion,probe the mechanism of astragus Preventing against cerebral ischemia-reprefusion injury. Methods:Methods of TUNEL and immunohistochenfistry were used respectively to measure neuronal apoptotmc cells and the expression of JUN protein in rats’ brains.Results:Compared with those in the sham-operated group, the numbers of neuronal apoptotic and JUN protein positive cells increased markedly in the model group.Compared with those in the model group, the nunlbers of neuronal apoptotic and JUN protein positive cells were less in the astragus group. Conclusion:Astragus could decrease neuronal apoptosis after cerebral ischemia and reperfusion by inhibiting the expression of JUN protein.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the effiects of astragus on neuronal apoptosis and the expression of JUN protein after cerebral ischemia and reperfusion,probe the mechanism of astragus Preventing against cerebral ischemia-reprefusion injury. Methods:Methods of TUNEL and immunohistochenfistry were used respectively to measure neuronal apoptotmc cells and the expression of JUN protein in rats’ brains.Results:Compared with those in the sham-operated group, the numbers of neuronal apoptotic and JUN protein positive cells increased markedly in the model group.Compared with those in the model group, the nunlbers of neuronal apoptotic and JUN protein positive cells were less in the astragus group. Conclusion:Astragus could decrease neuronal apoptosis after cerebral ischemia and reperfusion by inhibiting the expression of JUN protein.

Key concepts: TUNEL assay, Apoptosis, Medicine, Ischemia, Protein expression, Internal medicine, Immunohistochemistry, Gene

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The Effects of Astragus on the Neuronal Apoptosis and the Expression of JUN Protein after Cerebral Ischemia Reperfusion — Research Paper | ScholarLens