Extraction conditions of celery favone and its antioxidative activity

The conditions of leaching flavones from celery was studied by response surface analysis and the antioxidative effect of celery flavone extract was compared in vitro.The results showed that the optimal leaching conditions were 40% ethanol,ratio of solid to liquid 1∶15,extracting time 2.5 h,temperature 80 ℃.Under this condition,5.18% extract yield was gained with 4.3% flavone.Celery extract had strong activity of scavenging hydroxyl free radical of Featon reation and DPPH·,whose IC_(50) values were 10.1 (mg/L) and 8 mg/L respectively,and its activity was weaker than quercetin while stronger than vitamin C compared with vitamin C and quercetin.