The protective effect of Qingganlidan Oral Liquid in alcoholic liver injury

Objective: To study the protective effect of Qingganlidan Oral Liquid on alcoholic liver injury.Methods: The alcoholic liver injury model of rat was established by adopting alcohol,was administered intragastrically with Qingganlidan Oral Liquid of high-dose and low-dose respectively for 8 weeks,the serum content of AST,ALT,the liver content of MDA and GSH were measured,the liver histopathological changes were observed.Results: Qingganlidan Oral Liquid could significantly lower the serum content of AST,ALT,and there was obvious difference compared with model group(P0.01 or P0.05);the liver contents of MDA of high-dose and low-dose groups were lower than the model group,and the liver contents of GSH were higher than the model group,the liver histopathological changes significantly relieved than the model group.Conclusion: Qingganlidan Oral Liquid can effectively improve the alcoholic liver injury,and there was dose-effect relationship.