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2006•Chinese Journal of Natural MedicinesRequires access

Studies on the HPLC Fingerprint of Radix Glycyrrhizae

Yan Yong, Duan Tian

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Abstract

AIM: To study the quality disparities between wild and cultivated licorice root.METHOD: HPLC fingerprint of Radix Glycyrrhizae was established(Cromasil ODS column;0.1% phosphoric acid-acetonitrile as mobile phase;gradient elute,etc);The HPLC fingerprints of wild and cultivated licorice root was compared.RESULTS: Some peaks were identified by MS/MS;The fingerprints of them had lettle difference;The contents of two constituents in cultivated licorice root of different growing years were varied dynamically.CONCLUSION:The method is convenient,accurate and suitable for the quality control of Radix Glycyrrhizae.

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What this paper is about

AIM: To study the quality disparities between wild and cultivated licorice root.METHOD: HPLC fingerprint of Radix Glycyrrhizae was established(Cromasil ODS column;0.1% phosphoric acid-acetonitrile as mobile phase;gradient elute,etc);The HPLC fingerprints of wild and cultivated licorice root was compared.RESULTS: Some peaks were identified by MS/MS;The fingerprints of them had lettle difference;The contents of two constituents in cultivated licorice root of different growing years were varied dynamically.CONCLUSION:The method is convenient,accurate and suitable for the quality control of Radix Glycyrrhizae.

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Available abstract

AIM: To study the quality disparities between wild and cultivated licorice root.METHOD: HPLC fingerprint of Radix Glycyrrhizae was established(Cromasil ODS column;0.1% phosphoric acid-acetonitrile as mobile phase;gradient elute,etc);The HPLC fingerprints of wild and cultivated licorice root was compared.RESULTS: Some peaks were identified by MS/MS;The fingerprints of them had lettle difference;The contents of two constituents in cultivated licorice root of different growing years were varied dynamically.CONCLUSION:The method is convenient,accurate and suitable for the quality control of Radix Glycyrrhizae.

Key concepts: Gradient elution, Radix (gastropod), High-performance liquid chromatography, Fingerprint (computing), Chromatography, Phosphoric acid, Traditional medicine, Chemistry

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