[Effect of xiongshao capsule in treating 112 patients with coronary heart disease angina pectoris of xin-blood stasis syndrome].

OBJECTIVE: To observe the clinical effects and safety of Xiongshao Capsule (XSC) in treating patients with coronary heart disease angina of Xin-blood stasis syndrome. METHODS: Two hundred and forty patients were randomized equally into two groups, the treatment group and control group. They were treated with XSC and Xuefu Zhuyu Capsule respectively for 4 weeks. The therapeutic effect on angina pectoris, the dosage of nitroglycerin used and its withdrawal rate were observed, and changes in Chinese medical syndrome, electrocardiogram (ECG), blood lipids, and hemorrheologic figure were observed before and after treatment. RESULTS: The favorable effects on angina pectoris, ECG, Chinese medical syndromes, and clinical symptoms were observed in the treatment groups, showing significant statistical difference in improving angina pectoris and ECG to the control group (P < 0.05 or P < 0.01). CONCLUSION: XSC was effective and safe in treating coronary heart disease angina of Xin-blood stasis syndrome.