2004•Youjiang Medical JournalRequires access

The Protective effect of Radix Salvia Miltiorrhiza and SanQi Combine on Acute Hepatic Injury of carbon tetrachoride

Zhong Qiu

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Abstract

Objective To surry the protection of Radix Salvia Miltiorrhiza and SanQi combine against acute chemical hepatic injury.Methods Forming an acute chemical hepatic injury model of rat by using carbon tetrachoride (CCl 4),divided into five groups:the high ,medium and low dose of Radix Salvia Miltiorrhiza and San Qi combine group,normal control group and model control group .Measuring the serum acutive alanine transaminase(ALT),SDH,liver glycogen,liver coefficient and inspected the patholoical change of liver tissue,in order to evaluate the injure degree of liver and protective effect of the drug.Results Each rat with the treatment the serum ALT,SDH and liver coefficient were reduced(P0.01),liver glycogen compounding increased(P0.01),the pathological injure of liver tissue were significant improved. Conclusion Radix Sslvia Miltiorrhiza and San Qi combine could do good in curing injured liver tissue and regeneration of liver cell.

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Objective To surry the protection of Radix Salvia Miltiorrhiza and SanQi combine against acute chemical hepatic injury.Methods Forming an acute chemical hepatic injury model of rat by using carbon tetrachoride (CCl 4),divided into five groups:the high ,medium and low dose of Radix Salvia Miltiorrhiza and San Qi combine group,normal control group and model control group .Measuring the serum acutive alanine transaminase(ALT),SDH,liver glycogen,liver coefficient and inspected the patholoical change of liver tissue,in order to evaluate the injure degree of liver and protective effect of the drug.Results Each rat with the treatment the serum ALT,SDH and liver coefficient were reduced(P0.01),liver glycogen compounding increased(P0.01),the pathological injure of liver tissue were significant improved. Conclusion Radix Sslvia Miltiorrhiza and San Qi combine could do good in curing injured liver tissue and regeneration of liver cell.

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Available abstract

Objective To surry the protection of Radix Salvia Miltiorrhiza and SanQi combine against acute chemical hepatic injury.Methods Forming an acute chemical hepatic injury model of rat by using carbon tetrachoride (CCl 4),divided into five groups:the high ,medium and low dose of Radix Salvia Miltiorrhiza and San Qi combine group,normal control group and model control group .Measuring the serum acutive alanine transaminase(ALT),SDH,liver glycogen,liver coefficient and inspected the patholoical change of liver tissue,in order to evaluate the injure degree of liver and protective effect of the drug.Results Each rat with the treatment the serum ALT,SDH and liver coefficient were reduced(P0.01),liver glycogen compounding increased(P0.01),the pathological injure of liver tissue were significant improved. Conclusion Radix Sslvia Miltiorrhiza and San Qi combine could do good in curing injured liver tissue and regeneration of liver cell.

Key concepts: Salvia miltiorrhiza, Medicine, Radix (gastropod), Liver injury, Liver tissue, Traditional medicine, Glycogen, Carbon tetrachloride

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