Efficacy observation of Edaravone combined with Batroxobin in the treatment of acute cerebral infarction

Objective To explore the efficacy of Edaravone combined with Batroxobin in the treatment of acute cerebral infarction.Methods 90 patients with acute cerebral infarction were randomly divided into three groups:Batroxobin group 30 patients,Edaravone group of 30 patients,combination of Batroxobin and Edaravone treatment group 30 patients.The clinical efficacy,neurological deficit scores and changes of fibrinogen levels were compared before and after treatment.Results The effective rate of combination group was 83.3%,significantly higher than Edaravone group(53.3%) and Batroxobin group(50.0%)(P0.05).Neurological deficit scores and fibrinogen levels reduced after treatment(P0.01) in both group.Fibrinogen levels of combination group was significantly lower than that of the other two groups(P0.01).Conclusion In the treatment of acute cerebral infarction,the efficacy of Edaravone combined with Batroxobin was better than single use of edaravone or Batroxobin.