Hydroxycamptothecin Combining with Lifein In Treatment Of Malignant Pleural And Petitoneal Effusion

Objectice To evaluate the clinical efficacy and toxicity of Hydroxycamptothecin combining with Lifein in treatment of malignant peural and peritoneal effusion, thirty cases were considered. Methods The patients were extracted pleural and peritoneal effusion then injected Hydroxycamptothecin 20mg and Lifein30mg ocea week and above all for three to four weeks.Results Complete remission (CR) for five cases and partial remission (PR) for eighteen cases. The total effective rates were 76.7%. Conclusion It has synergetic effect when combine the Hydroxycamptothecin and Lifein to treat malignant pleural and peritoneal effusion. It can improve the cell immune of the body,decrease malignant pleural and peritoneal effusion and improve the improve the quality life.