Clinical features of elderly ischemic cerebrovascular disease patients

Objective To study the clinical features of elderly type 2diabetic patients with ischemic cerebrovascular disease(ICVD).Methods Four hundred elderly ischemic stroke patients were divided into ischemic stroke group(n=144),diabetes plus acute ischemic stroke group(n=256),and 102subjects undergoing physical examination served as a control group.Their serum HbA1c and hs-CRP level and carotid IMT were measured.Results The serum HbA1cand hs-CRP levels were significantly different in diabetes plus acute ischemic strore group,ischemic stroke group and control group[(8.16±2.47)%and(5.01±1.76)%vs(5.10±1.08)%,(4.23±2.76)ng/L and(3.42±2.02)ng/L vs(1.50±1.54)ng/L,P0.05].Age,hypertension,serum HbA1cand hs-CRP level were the independent risk factors for carotid atherosclerosis.The carotid atherosclerosis was severer in diabetes plus acute ischemic stroke group than in ischemic stroke group and control group(70.3%vs 46.5% and 8.8%,P0.05).The carotid IMT was positively related with the serum HbA1cand hs-CRP level(r=0.317,r=0.208,P0.05).Conclusion Carotid atherosclerotic plaques are closely related with serum HbA1cand hs-CRP level in elderly type 2 diabetic patients with ICVD.