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Uncertainty of Measurement in the HPLC Determination of Pseudoephedrine

Hezhan Zhang

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Abstract

Objective: Find out the effect factors of uncertainty by analyzing the uncertainty of measurement in determination of pseudoephedirine by HPLC and provide the evidence to evaluate the measurement. Method: Determinate the pseudoephedrine in syrup by HPLC and appraise the uncertainty according to JJF1059-1999. Result: The uncertainty of this test is 0.11 mg mL~(-1). Conclusion: It is found out that the uncertainty of this experiment is mainly caused by duplicated injected samples.

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What this paper is about

Objective: Find out the effect factors of uncertainty by analyzing the uncertainty of measurement in determination of pseudoephedirine by HPLC and provide the evidence to evaluate the measurement. Method: Determinate the pseudoephedrine in syrup by HPLC and appraise the uncertainty according to JJF1059-1999. Result: The uncertainty of this test is 0.11 mg mL~(-1). Conclusion: It is found out that the uncertainty of this experiment is mainly caused by duplicated injected samples.

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Available abstract

Objective: Find out the effect factors of uncertainty by analyzing the uncertainty of measurement in determination of pseudoephedirine by HPLC and provide the evidence to evaluate the measurement. Method: Determinate the pseudoephedrine in syrup by HPLC and appraise the uncertainty according to JJF1059-1999. Result: The uncertainty of this test is 0.11 mg mL~(-1). Conclusion: It is found out that the uncertainty of this experiment is mainly caused by duplicated injected samples.

Key concepts: Pseudoephedrine, Chemistry, Chromatography, Measurement uncertainty, High-performance liquid chromatography, Statistics, Ephedrine, Mathematics

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