Experimental study of zinc supplement on orthodontic alveolar bone remodeling in rabbits

AIM: To investigate the effect of zinc supplement on orthodontic tooth movement in rabbits. METHODS : The models of rabbits orthodontic tooth movement were established. Experimental group were received intramascular injection of 1% ZnSO 4 and control group with distilled water.Two weeks later, measure the distance of tooth movement and investigate the histological changes of orthodontic periodontal tissuse. RESULTS: In the experimental group, the distance of tooth movement was larger than that in the coutrol group( P 0.05). The histological changes showed that the osteogenesis and osteolysis of the alveolar bone appeared progessively active. CONCLUSION: Extra zinc supplement might be directly or indirectly promote the orthodontic alveolar bone remodeling.