Preparation and characteration of organic and inorganic sunscreens loaded nanostructured lipid carriers (NLC)
Yanling Chen
Abstract
Yanling Chen
Abstract
Ethylhexyl triazone(Uvinul T 150) and zinc oxide loaded nanostructured lipid carried were prepared by High Press Homogenization(HPH).At room temperature,the average particle sizes measured by Photon Correlation Spectroscopy(PCS) were in the range of 314 nm ± 4 nm,and the polydispersity index(PDI) were from 0.100 to 0.300.The pH of sunscreen formulation near to 7.00 was closed to the pH of man’s skin.The reservation of Uvinul T 150 of sunscreen formulation was in the range of 8.98 g / mL to 9.76 g / mL by RP-HPLC.The stability of storage time and temperature on the physicochemical properties of sunscreen formulation were investigated in details.
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Ethylhexyl triazone(Uvinul T 150) and zinc oxide loaded nanostructured lipid carried were prepared by High Press Homogenization(HPH).At room temperature,the average particle sizes measured by Photon Correlation Spectroscopy(PCS) were in the range of 314 nm ± 4 nm,and the polydispersity index(PDI) were from 0.100 to 0.300.The pH of sunscreen formulation near to 7.00 was closed to the pH of man’s skin.The reservation of Uvinul T 150 of sunscreen formulation was in the range of 8.98 g / mL to 9.76 g / mL by RP-HPLC.The stability of storage time and temperature on the physicochemical properties of sunscreen formulation were investigated in details.
Key concepts: Dispersity, Chemistry, Particle size, Chromatography, Zinc, Homogenization (climate), Nuclear chemistry, Analytical Chemistry (journal)