Pathological Effect and Mechanism of Enteral Nutrition at Different Time on Pancreas and Intestinal Tract of Rats with Severe Acute Pancreatitis

Objective To explore the pathological effect and mechanism of enteral nutrition at different time on pancreas and intestinal tract of rats with severe acute pancreatitis. Methods 84 rats were used to establish SAP model,and divided into two groups,the PN group( 21 cases) received routine treatment by parenteral nutrition,the EN group was randomly divided into 3 subgroups( 21 cases in each group),received EN at different time( the second day,the fourth day,the sixth day),to compare the pathological score of pancreas and intestinal tract. Results Compared with the PN group,the pathological score in EN group is lower( P 0. 01),and it is also different in the EN subgroups( P 0. 05); the EN is in favor of the intestinal tract,more earlier more better. Conclusion The enteral nutrition can improve the pathological situation of pancreas and intestinal tract,more earlier more sooner.