Clinical efficacy comparison of escitalopram treatment combined with aripiprazole on obsessive compulsive disorder.

Objective:To investigate the effectiveness and safety of escitalopram with or without aripiprazole in the treatment of obsessive-compulsive disorder.Method:60 patients with obsessive compulsive disorder were randomly assigned to receive escitalopram with or without aripiprazole.Effectiveness and adverse effect were assessed by Yale-Brown obsessive compulsive scale(Y-BOCS)and treatment emergent symptom scale(TESS),respectively.Results:Patients both received escitalopram and escitalopram with aripiprazole showed significant improvement by Y-BOCS scores after treatment,while the combination group showed a better outcome.There was no significant difference in TESS evaluation between the two groups.Conclusion:Escitalopram could effectively treat obsessive-compulsive disorder,while escitalopram combined with aripiprazole is more effective.