Determination of glomerular filtration rate in patients with early diabetic nephropathy

Objective To investigate the effect of the determination of glomerular filtration rate in treatment of early diabetic nephropathy. Methods Patients with early diabetic nephropathy and normal in our hospital from January 2012 to January 2014 were selected as a medical study,and divided into an early diabetes group and a normal group,30 cases in each group.The glomerular filtration rate between the two groups were determined and compared. Results GFR average index in normal albuminuria group and microalbuminuria group was higher than that in normal group, and difference in the two group compared with the normal group was significant(P 0.05);A large number of albuminuria GFR index was lower than that in the normal group,with significant difference(P 0.05);With UAER,diabetic patients with elevated BUN,Cr,and only a large number of albuminuria group of patients with BUN,Cr significant difference compared with the normal group(P 0.05). Conclusion Using the determination of glomerular filtration rate for early check in diabetic patients,the result can accurately reflect the status of early diabetic nephropathy in patients with renal damage,so as to provide reference for clinical treatment,is worthy of clinical application.