2013心血管病防治知识(学术版)Requires access

Clinical efficacy of levamlodipine besylate in treatment of primary hypertension

Guihu Zhao

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Abstract

Objective To investigate the clinical efficacy of levamlodipine besylate in the treatment of primary hypertension.Methods A total of 122 patients with primary hypertension who visited our hospital from February 2011 to February 2013 were randomly divided into study group and control group.The control group received sustained release tablets of nifedipine,while the study group received levamlodipine besylate.The treatment outcomes of the two groups(changes in blood pressure,overall response rate,and adverse reactions) were observed,analyzed,and compared.Results Both groups showed significant decreases in blood pressure after treatment(P0.05).The study group had a significantly higher overall response rate than the control group [91.80%(56/61) vs 80.33%(49/61),P0.05].The study group had a significantly lower incidence of adverse events than the control group [6.56%(4/61) vs 18.03%(11/61),P0.05].Conclusion The patients with primary hypertension have good treatment compliance and hypertension outcome and low incidence of adverse events when treated with levamlodipine besylate.Levamlodipine besylate holds promise for clinical application.

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Objective To investigate the clinical efficacy of levamlodipine besylate in the treatment of primary hypertension.Methods A total of 122 patients with primary hypertension who visited our hospital from February 2011 to February 2013 were randomly divided into study group and control group.The control group received sustained release tablets of nifedipine,while the study group received levamlodipine besylate.The treatment outcomes of the two groups(changes in blood pressure,overall response rate,and adverse reactions) were observed,analyzed,and compared.Results Both groups showed significant decreases in blood pressure after treatment(P0.05).The study group had a significantly higher overall response rate than the control group [91.80%(56/61) vs 80.33%(49/61),P0.05].The study group had a significantly lower incidence of adverse events than the control group [6.56%(4/61) vs 18.03%(11/61),P0.05].Conclusion The patients with primary hypertension have good treatment compliance and hypertension outcome and low incidence of adverse events when treated with levamlodipine besylate.Levamlodipine besylate holds promise for clinical application.

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Available abstract

Objective To investigate the clinical efficacy of levamlodipine besylate in the treatment of primary hypertension.Methods A total of 122 patients with primary hypertension who visited our hospital from February 2011 to February 2013 were randomly divided into study group and control group.The control group received sustained release tablets of nifedipine,while the study group received levamlodipine besylate.The treatment outcomes of the two groups(changes in blood pressure,overall response rate,and adverse reactions) were observed,analyzed,and compared.Results Both groups showed significant decreases in blood pressure after treatment(P0.05).The study group had a significantly higher overall response rate than the control group [91.80%(56/61) vs 80.33%(49/61),P0.05].The study group had a significantly lower incidence of adverse events than the control group [6.56%(4/61) vs 18.03%(11/61),P0.05].Conclusion The patients with primary hypertension have good treatment compliance and hypertension outcome and low incidence of adverse events when treated with levamlodipine besylate.Levamlodipine besylate holds promise for clinical application.

Key concepts: Medicine, Blood pressure, Adverse effect, Incidence (geometry), Anesthesia, Nifedipine, Internal medicine, Calcium

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