Early Diagnostic Valve of Cerebrospinal Fluid Cytology with Children Viral Encephalitis

Objective To investigate the value of examination of cerebrospinal fluid cytology(CSFC) in earlydiagnosis of children viral encephalitis.Methods Retrospective analysis of 123 patients with viral encephalitis in children with clinical data,including EEG,head CT,cerebrospinal fluid routine and biochemistry and CSFC examination,and data were performed and analyzed.Results The major early clinical symptoms were spirit of the poor in 102 cases(82.9%),fever in 80 cases(65.0%),headache in 79 cases(64.2%),nausea and vomiting in 78 cases(63.4%),seizure in 29 cases(23.6%).EEG and CT showed abnormality in 75.6%(93/123) and 21.5%(17/79) patients respectively.The abnormal cerebrospinal fluid routine and biochemistry was found in 45.5%(56/123) patients.The CSFC was abnormal in 91.1%(112/123) patients mainly with lymphatic cell changes(91.1%,102/123).The detection rate of CSFC was higher than that of cerebrospinal fluid routine or EEG(P0.05).Conclusion The clinical manifestation was variable in viral encephalitis and CSFC was the most important factor in the early diagnosis of viral encephalitis with the highest abnormality.