2011Zhongguo xin yao zazhiRequires access

Treatment of irritable bowel syndrome with trimebute maleate combined with medilac-S

Chen Fang-fang

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Abstract

Objective: To evaluate the therapeutic effect of trimebute maleate combined with medilac-S in the treatment of irritable bowel syndrome(IBS).Methods: Sixty patients with IBS were randomly divided into two groups(n=30 in each group).They were treated with 200 mg of trimebute maleate and 500 mg of medilac-S,po,tid;or with medilac-S,po,tid,alone(control group) for four weeks.The symptoms of patients,times and physical findings of stool were observed.Results: The overall efficacy rate was 90% in combination group,which was obviously higher than that in control group(73.33%,P0.05).The effect on abdominal pain and diarrhea were significantly better in combination group than in control group(P0.05).Conclusion: Trimebute maleate in combination with medilac-S is effective in the treatment of IBS.

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What this paper is about

Objective: To evaluate the therapeutic effect of trimebute maleate combined with medilac-S in the treatment of irritable bowel syndrome(IBS).Methods: Sixty patients with IBS were randomly divided into two groups(n=30 in each group).They were treated with 200 mg of trimebute maleate and 500 mg of medilac-S,po,tid;or with medilac-S,po,tid,alone(control group) for four weeks.The symptoms of patients,times and physical findings of stool were observed.Results: The overall efficacy rate was 90% in combination group,which was obviously higher than that in control group(73.33%,P0.05).The effect on abdominal pain and diarrhea were significantly better in combination group than in control group(P0.05).Conclusion: Trimebute maleate in combination with medilac-S is effective in the treatment of IBS.

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Available abstract

Objective: To evaluate the therapeutic effect of trimebute maleate combined with medilac-S in the treatment of irritable bowel syndrome(IBS).Methods: Sixty patients with IBS were randomly divided into two groups(n=30 in each group).They were treated with 200 mg of trimebute maleate and 500 mg of medilac-S,po,tid;or with medilac-S,po,tid,alone(control group) for four weeks.The symptoms of patients,times and physical findings of stool were observed.Results: The overall efficacy rate was 90% in combination group,which was obviously higher than that in control group(73.33%,P0.05).The effect on abdominal pain and diarrhea were significantly better in combination group than in control group(P0.05).Conclusion: Trimebute maleate in combination with medilac-S is effective in the treatment of IBS.

Key concepts: Irritable bowel syndrome, Diarrhea, Medicine, Gastroenterology, Internal medicine, Abdominal pain, Therapeutic effect

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