2013•Zhongguo yaofangRequires access
Analysis of the Distribution and Drug Resistance of Pathogens in Blood Cultures of Our Hospital from 2009 to 2012
Duan Yan-ya
Open publisher page 1 citations
Abstract
OBJECTIVE:To investigate the distribution and drug resistance of pathogens from positive blood culture in our hospital in order to guide clinical rational use of drugs.METHODS:By using retrospective analysis method,the distribution,composition and drug resistance of pathogens from positive blood culture were summarized statistically in our hospital from 2009 to 2012.RESULTS:Among 1 128 strains of isolated pathogens,Gram-positive bacteria accounted for 79.52%,Gram-negative bacteria accounted for 18.71% and fungi accounted for 1.77%.Top 3 pathogens were Staphylococcus epidermidis(42.64%),Staphylococcus haemolyticus(13.21%),Klebsiella pneumoniae(6.56%).Results from the sensitivity test confirmed that Gram-positive bacteria were highly sensitive to vancomycin and linezolid,and no drug-resistant strain was found.Gram-negative bacteria strains were the least resistant to imipenem,followed by amikacin.CONCLUSIONS:The drug resistance of pathogens from positive blood culture is serious.It is suggested that antibacterial agents be used rationally so as to enhance clinical therapeutic efficacy.