Apparent Diffusion Coefficient Value of Diffusion Weighted Imaging in Peritumoral Edema Regions for Differential Diagnosis of Brain Tumors

Objective To evaluate the value of diffusion-weighted imaging(DWI) in the diagnosis of intracranial tumors by analyzing the apparent diffusion coefficient(ADC)obtained from peritumoral edema.Materials and Meth-ods 82 patients with brain tumors underwent routine and diffusion-weighted MR imaging.ADC,relative apparent diffusion coefficient(rADC),exponential apparent diffusion coefficient(EADC),relative exponential apparent diffusion coefficient(rEADC) in peritumoral edematous tissues and tumoral parenchyma were compared in different tumors.Results ADC and rADC in peritumoral edema were significantly different among high-grade gliomas and low-grade gliomas,metastases,meningiomas,lymphoma.EADC and rEADC of perifocal edema were significantly different among high-grade gliomas and low-grade gliomas.Conclusion The ADC values in peritumoral edema is helpful in differentiating high-grade glioma from other brain tumors,and also valuable in grading gliomas.