Clinical study of the visual quality after implantation of an aspherical intraocular lens Acrysof IQ

Objective To observe the clinical effects after implantation of an aspherical intraocular lens Acrysof IQ.Design Prospective,randomized concurrent-controlled study.Participants 64 patients(64 eyes)with bilateral senile cataracts.Methods Pa- tients were operated with phacoemulsification and IOL implantation.They were divided randomly into 2 groups according to the table of random number:one group with Aerysof IQ(aspherical IOL)implantation and the other with Acrysof SN60AT(spherical IOL).Thor- ough ophthalmic examinations,including visual acuity,slit lamp examinations,fundoseopy,wavefront aberrometry,contrast sensitivity, were performed 1 week,1 month and 3 months after surgery.Main Outcome Measures Visual acuity,the best corrected visual acuity, spherical aberration(C 12),the root mean square of the total higher-order aberration(RMSh),and contrast sensitivity at 4 kinds of light backgrounds.Results At 1 postoperative month,RMSh(0.30±0.68μm)and C12(0.07,±0.04μm)in aspherical IOL group were signifi- cantly lower than those of the spherical IOL group(0.49±0.14μm,0.36±0.06μm)(P=0.00)with a 6.0 mm aperture.At 3 postoperative months the RMSh(0.30±0.07μm)and C12(0.06±0.06μm)in aspherical IOL group were significantly lower than those of the spherical IOL group(0.47±0.14μm,0.34±0.06μm)(P=0.00)with a 6.0 mm aperture.The asphefieal IOL(Acrysof IQ)provided statistically sig- nificant better contrast sensitivity at all spatial frequencies under mesopic conditions(3 cd/m~2)with and without glare(P0.05).Con- clasion The aspherical IOL(Aerysof IQ)can reduce RMSh and C12,providing better contrast sensitivity in mesopic conditions,thus can improve visual quality.(Ophthalmol CHN,2008,17:94-97)