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2011•Guangdong nongye kexueOpen access

Effects of Somatostatin on Expression of Stanniocalcin Gene in Mammary Gland of Rat

Yueying Wang

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Abstract

To investigate the effect of somatostatin on the expression of stanniocalcin gene in the mammary gland of rat,the lactating rats were divided into the control group,CS group and SS group,and the stanniocalcin gene in rat mammary gland was detected by using RT-PCR method.The results indicated that STC1 was expressed in the mammary gland,but there was no STC2 expression.Somatostatin down-regulated the expression of stanniocalcin gene in the mammary gland of the lactating rats,while cysteamine up-regulated the expression of stanniocalcin gene.The above results suggest that somatostatin and cysteamine may be involved in the regulation of calcium metabolism in the mammary gland and play an important role by STC1.

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What this paper is about

To investigate the effect of somatostatin on the expression of stanniocalcin gene in the mammary gland of rat,the lactating rats were divided into the control group,CS group and SS group,and the stanniocalcin gene in rat mammary gland was detected by using RT-PCR method.The results indicated that STC1 was expressed in the mammary gland,but there was no STC2 expression.Somatostatin down-regulated the expression of stanniocalcin gene in the mammary gland of the lactating rats,while cysteamine up-regulated the expression of stanniocalcin gene.The above results suggest that somatostatin and cysteamine may be involved in the regulation of calcium metabolism in the mammary gland and play an important role by STC1.

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Available abstract

To investigate the effect of somatostatin on the expression of stanniocalcin gene in the mammary gland of rat,the lactating rats were divided into the control group,CS group and SS group,and the stanniocalcin gene in rat mammary gland was detected by using RT-PCR method.The results indicated that STC1 was expressed in the mammary gland,but there was no STC2 expression.Somatostatin down-regulated the expression of stanniocalcin gene in the mammary gland of the lactating rats,while cysteamine up-regulated the expression of stanniocalcin gene.The above results suggest that somatostatin and cysteamine may be involved in the regulation of calcium metabolism in the mammary gland and play an important role by STC1.

Key concepts: Mammary gland, Somatostatin, Internal medicine, Endocrinology, Gene expression, Biology, Cysteamine, Gene

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Effects of Somatostatin on Expression of Stanniocalcin Gene in Mammary Gland of Rat — Research Paper | ScholarLens