ScholarLens Back to search
2014•Zhongguo shiyan fangjixue zazhiRequires access

Optimization of Extraction Technology for Couplet Medicines of Scutellariae Radix and Paeoniae Radix Alba

Xin Zhao

Open publisher page 0 citations

Abstract

Objective: To optimize extraction process of couplet medicines of Scutellariae Radix and Paeoniae Radix Alba. Method: With contents of baicalin and paeoniflorin as indicators,orthogonal test was adopted to investigate influence of the amount of solvent,ethanol concentration,extracting times and time on mixed extraction technology. HPLC was used to determine contents of baicalin and paeoniflorin with mobile phase of methanol-water-acetic acid( 35∶ 64∶ 1) and detection wavelength at 244 nm. Result: Optimum conditions were as follows: extracted twice with 12 times the amount of 50% ethanol for 1. 5 h per time; mass fractions of baicalin and paeoniflorin were 16. 75% and 3. 22%,respectively. Conclusion: This optimized process was stable and feasible,Scutellariae Radix had a certain auxo-action for extraction of paeoniflorin.

About this research paper

What this paper is about

Objective: To optimize extraction process of couplet medicines of Scutellariae Radix and Paeoniae Radix Alba. Method: With contents of baicalin and paeoniflorin as indicators,orthogonal test was adopted to investigate influence of the amount of solvent,ethanol concentration,extracting times and time on mixed extraction technology. HPLC was used to determine contents of baicalin and paeoniflorin with mobile phase of methanol-water-acetic acid( 35∶ 64∶ 1) and detection wavelength at 244 nm. Result: Optimum conditions were as follows: extracted twice with 12 times the amount of 50% ethanol for 1. 5 h per time; mass fractions of baicalin and paeoniflorin were 16. 75% and 3. 22%,respectively. Conclusion: This optimized process was stable and feasible,Scutellariae Radix had a certain auxo-action for extraction of paeoniflorin.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To optimize extraction process of couplet medicines of Scutellariae Radix and Paeoniae Radix Alba. Method: With contents of baicalin and paeoniflorin as indicators,orthogonal test was adopted to investigate influence of the amount of solvent,ethanol concentration,extracting times and time on mixed extraction technology. HPLC was used to determine contents of baicalin and paeoniflorin with mobile phase of methanol-water-acetic acid( 35∶ 64∶ 1) and detection wavelength at 244 nm. Result: Optimum conditions were as follows: extracted twice with 12 times the amount of 50% ethanol for 1. 5 h per time; mass fractions of baicalin and paeoniflorin were 16. 75% and 3. 22%,respectively. Conclusion: This optimized process was stable and feasible,Scutellariae Radix had a certain auxo-action for extraction of paeoniflorin.

Key concepts: Paeoniflorin, Baicalin, Radix (gastropod), Chromatography, Chemistry, Traditional medicine, Extraction (chemistry), Paeonia lactiflora

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Optimization of Extraction Technology for Couplet Medicines of Scutellariae Radix and Paeoniae Radix Alba — Research Paper | ScholarLens