2003•ZhongchengyaoRequires access

Extraction of paeoniflorin in Radix Paeoniae Alba

Fang Liu

Abstract

Objective: To establish an extraction of paeoniflorin from Radix Paeoniae Alba as traditional Chinese medicine. Methods: The paeoniflorin in Radix Paeoniae Alba was taken as a evaluating marker and was determined by HPLC, the effects of different solvents and extraction on extraction efficiency of the paeoniflorin were systematically investigated. And also the orthogonal test was further used to optimize the extracting conditions. Results: The reflux extraction with 80% ethanol seven times as much as the Radix Paeoniae Alba amount for 2 h and twice was more effective. Conclusion: The kinds of solvent and method of extraction have a great influence upon the extracting efficiency of paeoniflorin.

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Key concepts: Paeoniflorin, Radix (gastropod), Chromatography, Extraction (chemistry), Chemistry, Traditional medicine, High-performance liquid chromatography, Medicine