Mechanical ventilation for acute severe bronchial asthma

Objective To evaluate the method and efficacy of mechanical ventilation treating acute severe bronchial asthma.Methods Fifteen cases in 246 cases of acute severe bronchial asthma during Jan 2001 and Nov 2004 were done mechanical ventilation and general medical treatment at the same time.The ventilation mode of 13 cases of mechanical ventilation via tracheal cannula were A/C and SIMV+PSV (VT 6-8ml/kg,RR 10-12 per minute,I/E1:2,inspiratory press25cmH 2O,inspiratory duration 0.7s～ 1.0s).The ventilation mode of 2 cases of mechanical ventilation was BIPAP via face mask.Results Fifteen patients were treated successfully.The amelioration of symptoms and signs started 1.25 hour after mechanical ventilation.The symptom score was not more than two 24 hours after mechanical ventilation.The duration of mechanical ventilation was 59.8 hours.The parameter of blood gas analysis was normal and PEF was increased significantly (P 0.01) after treatment.Conclusions Mechanical ventilation was effective method to treat acute severe bronchial asthma.It should be noticed on proper indication,mode and parameter.