Efficacy of Shenqi Dihuang Decoction Combined with Western Medicine in Treatment of Qi-Yin Deficiency Type of Lupus Nephritis

Objective: To investigate the efficacy of Shenqi Dihuang Decoction combined with western medicine in the treatment of Qi- Yin deficiency type of lupus nephritis and to provide reference for clinical diagnosis and treatment. Methods: 56 cases of patients with lupus nephritis of Qi- Yin deficiency according to random number table were randomly divided into control group( n = 28) and treatment group( n = 28). The control group received prednisone tablets and the treatment group took Shenqi Dihuang Decoction on the basis of the control group. Three months was a course of treatment. Lupus activity indexes were observed before and after treatment. The serum vascular endothelial cell index,physical and chemical testing indicators( erythrocyte sedimentation rate,serum creatinine,24 h urine protein) were observed.Results: The total effective rate( 92. 86%) in the treatment group was significantly higher than that of the control group( 71. 43%) and there was a significant difference( P 0. 05). The improvement after treatment of lupus activity index,serum vascular endothelial cell index,physical and chemical testing indicators( erythrocyte sedimentation rate,serum creatinine,24 h urine protein) in the treatment group were better than those of the control group and there was significant difference( P 0. 05). Conclusion: Modified Shenqi Dihuang Decoction combined with western medicine can significantly relieve symptoms and improve laboratory parameters of Qi- Yin deficiency type of lupus nephritis and it is worthy of promotion.