2005•Unpublished venueRequires access

Expression and relation of vascular endothelial growth factor and angiogenesis in non-small cell lung cancer.

Yang Shi-jiang

Abstract

Objective To evaluate the expression and relation between VEGF and angiogenesis in different stages of non-small cell lung cancer.Methods The expression of VEGF and angiogenesis were detected using immunohistochemical method in 79 lung cancer tissue and 12 normal tissue.The result was analyzed with immunohistochemical image-analysis system.Results VEGF and angiogenesis in NSCLC were significantly higher than that in normal pulmonary tissue.The expression of VEGF and angiogenesis was closely related to P-TNM stages,but there was no difference between adenocarcinoma and squamouscarcinoma.Conclusion A positive correlation was found between VEGF and angiogenesis in NSCLC.

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Key concepts: Angiogenesis, Immunohistochemistry, Lung cancer, Adenocarcinoma, Vascular endothelial growth factor, Medicine, Pathology, Lung