Clinical efficacy of wavefront-guided laser in situ keratomileusis for myopia

Objective To investigate the outcome of wavefront-guided laser in situ keratomileusis(LASIK) for myopia.Methods Forty eyes in 21 patients with myopia undergoing wavefront-guided LASIK were collected as wavefront group,and 31 eyes in 16 patients with myopia receiving LASIK were chosen as control group.All patients were followed-up for one year.Visual acuity,refraction and high-order aberrations(HOAs)were examined before and after operation.The outcomes between two groups were compared.Results After followed-up,uncorrected visual acuity(UCVA)of all eyes were higher than 0.8.UCVA achieved 1.0 or better in 97.5% of eyes in wavefront group and 96.8% in control group.UCVA achieved 1.5 or better in 35.0% of eyes in wavefront group and 16.1% in control group.A total of 37.5% of eyes exceeded the preoperative best corrected visual acuity(BCVA) in wavefront group and only 19.4% in control group,but the difference was not significant(P 0.05).The eyes with postoperative refractions within ± 0.5D and within ± 1.0D accounted for 75% and 95% in wavefront group,and 77.4% and 93.5% in control group,respectively,but there was no significant difference in postoperative refractions between two groups(P 0.05).One year after the operation,total HOA,coma and spherical values increased in two groups,but the values were lower in wavefront group than in control group(P 0.05).Conclusion Compared with conventional LASIK,wavefront-guided LASIK has no advantage in improving uncorrected visual acuity,but wavefront-guided LASIK is more efficient to reduce the higher order aberration after operation.