Determination and clinical analysis of immune function of 117 infants infected with mycoplasma pneumoniae.

Objective To investigate the immune function and clinical feature of 117 child cases with Mycoplasma Pneumoniae. Methods Immune function of the 117 child cases with mycoplasma pneumoniae, IgM or IgG positive ,fever, cough was determined with immunologic approach and its clinical feature was observed and analyzed. Results The results showed the level of CD3, CD4 (51.63±5.74, 33.05±4.28) in children with mycoplasma pneumoniae was obviously lower than that of the normal control (66.32±5.17, 40.95±4.82, P 0. 05 ), and there was no significant difference in immunoglobulin in serum compared with the normal (P 0.05 ) of 117 child cases with mycoplasma pneumoniae, there was 98 cases sufferd from intermittent coughing and expectoration, 54 cases had low- grade fever night- sweat, 39 cases had diarrhea, 7 cases had kidney damage, 16 cases had liver damage, 8 cases had skin and mucosa damage, 5 cases had arthralgia, 11 electrocardiographic abnormality cases, and 91 cases were misdiagnosised as other deseases. Conclusion Cellular immune function of children with mycoplasma pneumoniae was reduced and no change in humoral immunity function was observed. The clinical manifestations of children with mycoplasma pneumoniae displayed multiplicity and complicated. Children with mycoplasma pneumoniae should check blood promptly for MP - IgM for early diagnosis and curative effect of anti - infection alone was not satisfactory. It was useful for macrolides gathering with cephalosporins to treat mycoplasma pneumoniae.