Clinical efficacy of tiotropium bromide combined with salmeterol fluticasone propionate in treatment of chronic obstructive pulmonary disease

Objective To investigate the effect of tiotropium bromide combined with salmeterol fluticasone propionate for chronic obstructive pulmonary disease. Methods Eighty-eight cases of patients were randomly divided into two groups, the observation group (44 cases) were used tiotropium bromide combined with salmeterol fluticasone propionate, the control group (44 cases) were used only tiotropium bromide, after 2 weeks the pulmonary function, activities of daily living (ADL) and the score of 6 min walk distance were compared. Results The observation group with FEV1 and FVC were higher than control group (P 0.05), FEV 1 /FVC and FEV 1 percentage were higher than control group (P 0.05), activities of daily living score was higher than control group ( P 0.05), and 6 min walking distance was longer than control group (P 0.05). Conclusion Tiotropium bromide combined with combined with salmeterol fluticasone propionate for chronic obstructive pulmonary disease can accelerate the improvement of pulmonary function and improve patients' life quality, so it is worthy of clinical application.