2010•Chinese Journal of Veterinary DrugRequires access

Development of Rabies Inactivated Vaccine with a New Type Adjuvant

Xiaofeng Guo

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Abstract

Recombinant HEP-dG rabies virus stock was rescued by the technique of reverse genetics,inactivated rabies vaccines with a new type adjuvant for immune test were conducted in mice and the minimum immune dose test were conducted in beagle.The results demonstrated that recombinant HEP-dG rabies virus strain has good immunogenicity,and the rabies inactivated vaccines were effective and protective.

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What this paper is about

Recombinant HEP-dG rabies virus stock was rescued by the technique of reverse genetics,inactivated rabies vaccines with a new type adjuvant for immune test were conducted in mice and the minimum immune dose test were conducted in beagle.The results demonstrated that recombinant HEP-dG rabies virus strain has good immunogenicity,and the rabies inactivated vaccines were effective and protective.

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Available abstract

Recombinant HEP-dG rabies virus stock was rescued by the technique of reverse genetics,inactivated rabies vaccines with a new type adjuvant for immune test were conducted in mice and the minimum immune dose test were conducted in beagle.The results demonstrated that recombinant HEP-dG rabies virus strain has good immunogenicity,and the rabies inactivated vaccines were effective and protective.

Key concepts: Rabies, Immunogenicity, Virology, Rabies virus, Adjuvant, Recombinant DNA, Duck embryo vaccine, Rabies vaccine

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